Overview

  • Product name
  • Description
    Rabbit polyclonal to ADCY3
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse, Chinese hamster
  • Immunogen

    Synthetic peptide:

    PAAFPNGSSVTLPHQVVDNP

    conjugated to KLH by a N terminal Cysteine residue linker, corresponding to C terminal amino acids 1125-1144 of Rat ADCY3.

  • Positive control
    • Rat olfactory epithelium and frontal cortex lysates; Mixed neuron-glial cultures.

Properties

Applications

Our Abpromise guarantee covers the use of ab125093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/10000. Detects a band of approximately 160-200 kDa (predicted molecular weight: 129 kDa).
ICC/IF 1/500 - 1/1000.

Target

  • Function
    Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.
  • Tissue specificity
    Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
  • Sequence similarities
    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    Contains 2 guanylate cyclase domains.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AC-III antibody
    • AC3 antibody
    • ADCY3 antibody
    • ADCY3_HUMAN antibody
    • adenylate cyclase 3 antibody
    • Adenylate cyclase antibody
    • Adenylate cyclase type 3 antibody
    • Adenylate cyclase type III antibody
    • Adenylyl cyclase 3 antibody
    • ATP pyrophosphate lyase antibody
    • ATP pyrophosphate-lyase 3 antibody
    • olfactive type antibody
    see all

Images

  • All lanes : Anti-ADCY3 antibody (ab125093) at 1/5000 dilution

    Lane 1 : Rat olfactory epithelium lysate
    Lane 2 : Rat frontal cortex lysate


    Predicted band size : 129 kDa
  • ab125093, at 1/500, staining ADCY3 in mixed neuron-glial cultures by Immunofluorescence (red). A mouse monoclonal antibody staining of aII-spectrin (green) is also shown.

References

ab125093 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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