Anti-Adenovirus E1A antibody (ab13324)

Overview

  • Product nameAnti-Adenovirus E1A antibody
    See all Adenovirus E1A primary antibodies
  • Description
    Sheep polyclonal to Adenovirus E1A
  • Tested applicationsSuitable for: WBmore details
  • Immunogen

    Fusion protein.

  • Positive control
    • Whole extract of 293 cells.
  • General notesStorage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab13324 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 10 µg/ml. Predicted molecular weight: 300 kDa.

Target

  • RelevanceThe early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
  • Cellular localizationNuclear
  • Alternative names
    • Control protein E1A antibody
    • E1A antibody

References for Anti-Adenovirus E1A antibody (ab13324)

ab13324 has not yet been referenced specifically in any publications.

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