The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
1/50 - 1/100.
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.
Involvement in disease
Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency [MIM:612631].
ab71621 at 1/50 dilution, staining Adenylate Kinase 1 in human hepatocarcinoma by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.