Anti-Adiponectin Receptor 1 antibody (ab125459)

Overview

  • Product nameAnti-Adiponectin Receptor 1 antibody
    See all Adiponectin Receptor 1 primary antibodies
  • Description
    Rabbit polyclonal to Adiponectin Receptor 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Goat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within the N terminal amino acids 37-86 (KGKRVIANPP KAEEEQTCPV PQEEEEEVRV LTLPLQAHHA MEKMEEFVYK) of the Human Adiponectin Receptor 1 protein (NP_057083).

Properties

Applications

Our Abpromise guarantee covers the use of ab125459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 43 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionReceptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
  • Tissue specificityWidely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
  • Sequence similaritiesBelongs to the ADIPOR family.
  • DomainThe N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • Cellular localizationMembrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACDCR1 antibody
    • ADIPO R1 antibody
    • Adiponectin receptor protein 1 antibody
    • ADIPOR 1 antibody
    • Adipor1 antibody
    • ADR1_HUMAN antibody
    • CGI 45 antibody
    • CGI 45 protein antibody
    • CGI-45 antibody
    • CGI45 antibody
    • CGI45 protein antibody
    • FLJ25385 antibody
    • FLJ42464 antibody
    • PAQR1 antibody
    • Progestin and adipoQ receptor family member I antibody
    • TESBP1A antibody
    see all

Anti-Adiponectin Receptor 1 antibody images

  • Anti-Adiponectin Receptor 1 antibody (ab125459) at 1 µg/ml (Anti-ADIPOR1 Antibody) + 293T cell lysates

    Predicted band size : 43 kDa

References for Anti-Adiponectin Receptor 1 antibody (ab125459)

ab125459 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"