Anti-Adiponectin Receptor 2 antibody (ab113538)

Overview

  • Product nameAnti-Adiponectin Receptor 2 antibody
    See all Adiponectin Receptor 2 primary antibodies
  • Description
    Rabbit polyclonal to Adiponectin Receptor 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Macaque Monkey, Gorilla
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Adiponectin Receptor 2.

  • Positive control
    • This antibody gave a positive signal in Human Liver tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab113538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).

Target

  • FunctionReceptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
  • Tissue specificityHighly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
  • Sequence similaritiesBelongs to the ADIPOR family.
  • DomainThe N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • Cellular localizationMembrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • Database links
  • Alternative names
    • PAQR2 antibody
    • ACDCR2 antibody
    • Adiponectin receptor protein 2 antibody
    • Adipor2 antibody
    • ADR2_HUMAN antibody
    • Progestin and adipoQ receptor family member II antibody
    see all

Anti-Adiponectin Receptor 2 antibody images

  • Anti-Adiponectin Receptor 2 antibody (ab113538) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 1 minute

References for Anti-Adiponectin Receptor 2 antibody (ab113538)

ab113538 has not yet been referenced specifically in any publications.

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