Overview

  • Product nameAnti-AdSS 2 antibody
    See all AdSS 2 primary antibodies
  • Description
    Rabbit polyclonal to AdSS 2
  • Tested applicationsSuitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    antigen sequence: KLDGEIIPHI PANQEVLNKV EVQYKTLPGW NTDISNARAF KELPVNAQNY VRFIEDELQI PVKWIGVGKS RESM, corresponding to amino acids 379-452 of Human AdSS 2.

  • Positive control
    • Human colon tissue; RT-4 and U-251 MG cell lysates; Human Liver and Tonsil lysates; U-251MG cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab121810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

Target

  • FunctionPlays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  • PathwayPurine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.
  • Sequence similaritiesBelongs to the adenylosuccinate synthetase family.
  • Cellular localizationCytoplasm. Partially associated with particulate fractions.
  • Information by UniProt
  • Database links
  • Alternative names
    • (Ade(-)H, complement of antibody
    • acidic isozyme antibody
    • ADEH antibody
    • Adenylosuccinate synthetase (Ade(-)H complementing) antibody
    • Adenylosuccinate synthetase acidic isozyme antibody
    • Adenylosuccinate synthetase antibody
    • Adenylosuccinate synthetase isozyme 2 antibody
    • Adenylosuccinate synthetase liver isozyme antibody
    • AdSS 2 antibody
    • ADSS antibody
    • AMPSase 2 antibody
    • IMP--aspartate ligase 2 antibody
    • L-type adenylosuccinate synthetase antibody
    • liver isozyme antibody
    • PURA2_HUMAN antibody
    see all

Anti-AdSS 2 antibody images

  • ab121810, at 1/40 dilution, staining AdSS 2 in paraffin-embedded Human colon tissue by Immunohistochemistry.
  • All lanes : Anti-AdSS 2 antibody (ab121810) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate
  • ab121810, at 4µg/ml, staining AdSS 2 in U-251MG cells by Immunofluorescence.

References for Anti-AdSS 2 antibody (ab121810)

ab121810 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"