Overview

  • Product name
  • Description
    Rabbit polyclonal to ADSSL1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 143-192 (VDGLQEVQRQ AQEGKNIGTT KKGIGPTYSS KAARTGLRIC DLLSDFDEFS) of Human ADSSL1, NP_689541.

  • Positive control
    • Fetal muscle lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab85586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately <20, 50 kDa (predicted molecular weight: 50 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  • Tissue specificity
    Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors.
  • Pathway
    Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.
  • Sequence similarities
    Belongs to the adenylosuccinate synthetase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adenylosuccinate synthase like 1 antibody
    • Adenylosuccinate synthetase antibody
    • Adenylosuccinate synthetase isozyme 1 antibody
    • AdSS 1 antibody
    • ADSS1 antibody
    • ADSSL1 antibody
    • AMPSase 1 antibody
    • basic isozyme antibody
    • IMP aspartate ligase 1 antibody
    • IMP--aspartate ligase 1 antibody
    • M-type adenylosuccinate synthetase antibody
    • muscle isozyme antibody
    • PURA1_HUMAN antibody
    see all

Anti-ADSSL1 antibody images

  • Anti-ADSSL1 antibody (ab85586) at 1 µg/ml + fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 50 kDa
    Observed band size : 50 kDa
    Additional bands at : <22 kDa. We are unsure as to the identity of these extra bands.

References for Anti-ADSSL1 antibody (ab85586)

ab85586 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab85586.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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