Overview

  • Product name
    AF-DX 384
  • Description
    M2/M4 antagonist
  • Biological description
    M2/M4 receptor antagonist (Kd values are 1 (M2), 2.2 (M4), 15 (M3) and 55 nM (M1)). Low blood-brain barrier permeability.
  • Purity
    > 95%

Properties

References

This product has been referenced in:
  • Mickala P  et al. In vivo binding, pharmacokinetics and metabolism of the selective M2 muscarinic antagonists [3H]AF-DX 116 and [3H]AF-DX 384 in the anesthetized rat. Nucl Med Biol 23:173-9 (1996). Read more (PubMed: 8868291) »
  • Miller JH  et al. Binding of [3H]AF-DX 384 to cloned and native muscarinic receptors. J Pharmacol Exp Ther 259:601-7 (1991). Read more (PubMed: 1941609) »
  • Dörje F  et al. Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J Pharmacol Exp Ther 256:727-33 (1991). Read more (PubMed: 1994002) »

See 0 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120146.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up