Overview

  • Product nameAnti-AF10 antibody
    See all AF10 primary antibodies
  • Description
    Rabbit polyclonal to AF10
  • Tested applicationsSuitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) from the C-terminal region of AF10, conjugated to KLH.

  • Positive control
    • Jurkat cell lysate Human testis tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab71448 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 109 kDa (predicted molecular weight: 109 kDa).
IHC-P 1/10 - 1/50.

Target

  • FunctionProbably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.
  • Tissue specificityExpressed abundantly in testis.
  • Involvement in diseaseA chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein.
    A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.
  • Sequence similaritiesContains 1 C2HC pre-PHD-type zinc finger.
    Contains 2 PHD-type zinc fingers.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AF 10 antibody
    • AF10 antibody
    • AF10_HUMAN antibody
    • ALL 1 fused gene from chromosome 10 antibody
    • ALL1 fused gene from chromosome 10 antibody
    • ALL1-fused gene from chromosome 10 protein antibody
    • DKFZp686E10210 antibody
    • MGC75086 antibody
    • MLLT 10 antibody
    • MLLT10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog Drosophila) translocated to 10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia translocated to 10 antibody
    • OTTHUMP00000045273 antibody
    • Protein AF 10 antibody
    • Protein AF-10 antibody
    • Protein AF10 antibody
    • Type I AF10 protein antibody
    see all

Anti-AF10 antibody images

  • Anti-AF10 antibody (ab71448) at 1/100 dilution + Jurkat cell lysate at 12.5 µg

    Predicted band size : 109 kDa
    Observed band size : 109 kDa
    Additional bands at : 25 kDa,45 kDa,55 kDa. We are unsure as to the identity of these extra bands.
  • Formalin-fixed and paraffin-embedded human testis tissue labelled with ab71448 at 1/10 dilution. DAB staining.

References for Anti-AF10 antibody (ab71448)

ab71448 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71448.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"