Overview

  • Product name
    Anti-AF10 antibody - C-terminal
    See all AF10 primary antibodies
  • Description
    Rabbit polyclonal to AF10 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within C terminal amino acids 965-1027 of Human AF10 (UniProt ID: P55197).

  • Positive control
    • A431, H1299, HeLa, HepG2 whole cell lysate; SCC xenograft
  • General notes
    Keep as a concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab155205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 109 kDa.
IHC-P 1/100 - 1/1000. Suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).

Target

  • Function
    Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.
  • Tissue specificity
    Expressed abundantly in testis.
  • Involvement in disease
    A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein.
    A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.
  • Sequence similarities
    Contains 1 C2HC pre-PHD-type zinc finger.
    Contains 2 PHD-type zinc fingers.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AF 10 antibody
    • AF10 antibody
    • AF10_HUMAN antibody
    • ALL 1 fused gene from chromosome 10 antibody
    • ALL1 fused gene from chromosome 10 antibody
    • ALL1-fused gene from chromosome 10 protein antibody
    • DKFZp686E10210 antibody
    • MGC75086 antibody
    • MLLT 10 antibody
    • MLLT10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog Drosophila) translocated to 10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia translocated to 10 antibody
    • OTTHUMP00000045273 antibody
    • Protein AF 10 antibody
    • Protein AF-10 antibody
    • Protein AF10 antibody
    • Type I AF10 protein antibody
    see all

Images

  • Anti-AF10 antibody - C-terminal (ab155205) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 109 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded SCC xenograft tissue labeling AF10 with ab155205 at 1/100 dilution.

References

ab155205 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab155205.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up