Overview

  • Product name
  • Description
    Rabbit polyclonal to AFF2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Chimpanzee
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (DLFDFFRDWD LEQQCHYEQD RSALKKREWE RRNQEVQQED DLFSSGFDLF) of Human AFF2 (NP_002016).

  • Positive control
    • OVCAR-3 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab94564 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 145 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.
  • Tissue specificity
    Brain (most abundant in hippocampus and amygdala), placenta and lung.
  • Involvement in disease
    Mental retardation, X-linked, associated with fragile site FRAXE
  • Sequence similarities
    Belongs to the AF4 family.
  • Cellular localization
    Nucleus speckle. When splicing is inhibited, accumulates in enlarged speckles.
  • Information by UniProt
  • Database links
  • Alternative names
    • AF4/FMR2 family member 2 antibody
    • AF4/FMR2 family, member 2 antibody
    • AFF2 antibody
    • AFF2_HUMAN antibody
    • FMR2 antibody
    • FMR2P antibody
    • Fragile X E mental retardation syndrome protein antibody
    • fragile X mental retardation 2 antibody
    • Fragile X mental retardation 2 protein antibody
    • fragile X mental retardation gene associated with FRAXE antibody
    • FRAXE antibody
    • mild or borderline mental retardation antibody
    • MRX2 antibody
    • OTTHUMP00000024204 antibody
    • OX19 antibody
    • Protein FMR-2 antibody
    • Protein Ox19 antibody
    see all

Anti-AFF2 antibody images

  • Anti-AFF2 antibody (ab94564) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR-3 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 145 kDa

References for Anti-AFF2 antibody (ab94564)

ab94564 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94564.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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