Overview

  • Product nameAnti-AGA antibody
  • Description
    Rabbit polyclonal to AGA
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Guinea pig, Cow, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 138-187 (SMGFINEDLS TTASQALHSD WLARNCQPNY WRNVIPDPSK YCGPYKPPGI) of Human AGA (NP_001165459).

  • Positive control
    • Human placenta lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferConstituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab115852 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
  • Involvement in diseaseDefects in AGA are the cause of aspartylglucosaminuria (AGU) [MIM:208400]. AGU is an inborn lysosomal storage disease. Clinical features of AGU include mild to severe mental retardation manifesting from the age of 2, coarse facial features and mild connective tissue abnormalities. This recessively inherited disease is overrepresented in the Finnish population.
  • Sequence similaritiesBelongs to the Ntn-hydrolase family.
  • Cellular localizationLysosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Aga antibody
    • AGU antibody
    • Aspartylglucosaminidase antibody
    • Aspartylglucosylamine deaspartylase antibody
    • Aspartylglycosaminuria antibody
    • ASPG_HUMAN antibody
    • ASRG antibody
    • GA antibody
    • Glycosylasparaginase antibody
    • Glycosylasparaginase beta chain antibody
    • N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase antibody
    • N4 (N acetyl beta glucosaminyl) L asparagine amidase antibody
    • N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase antibody
    see all

Anti-AGA antibody images

  • Anti-AGA antibody (ab115852) at 1 µg/ml + Human placenta lysate at 10 µg

    Predicted band size : 37 kDa

References for Anti-AGA antibody (ab115852)

ab115852 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"