Anti-AGBL1 antibody (ab121034)

Overview

• Product name
  Anti-AGBL1 antibody
  See all AGBL1 primary antibodies
• Description
  Goat polyclonal to AGBL1

  This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

• Species reactivity
  
  Predicted to work with: Mouse, Rat, Cow, Dog, Human
• Immunogen

  Synthetic peptide:

  C-RPYQVITARVHPGE

  with a Cysteine residue linker, corresponding to internal sequence amino acids 748-761 of Human AGBL1 (NP_689549.2).

  Run BLAST with Run BLAST with

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• Storage buffer
  pH: 7.30
  Preservative: 0.02% Sodium azide
  Constituents: 99% Tris buffered saline, 0.5% BSA
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Purification notes
  ab121034 is purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide.
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Cell Biology
  • Proteolysis / Ubiquitin
  • Proteolytic enzymes
  • Other proteases

Associated products

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

Applications

Target

• Function
  Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
• Sequence similarities
  Belongs to the peptidase M14 family.
• Cellular localization
  Cytoplasm > cytosol.

• Target information above from: UniProt accession Q96MI9 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 479034 Dog
  • Entrez Gene: 123624 Human
  • Entrez Gene: 244071 Mouse
  • Entrez Gene: 308724 Rat
  • Omim: 615496 Human
  • SwissProt: Q96MI9 Human
  • SwissProt: Q09M05 Mouse
  • Unigene: 679833 Human

  • Unigene: 322829 Mouse

  see all
• Alternative names
  • Agbl1 antibody
  • ATP/GTP-binding protein-like 1 antibody
  • Carboxypeptidase 4, cytosolic antibody

  • CBPC4_HUMAN antibody
  • Ccp4 antibody
  • Cytosolic carboxypeptidase 4 antibody
  • D430020F16 antibody
  • EG244071 antibody
  • FLJ32310 antibody
  • MGC149239 antibody
  • Nna1 l1 antibody
  • RGD1560280 antibody

  see all

Protocols

• Western blot protocols