Overview

  • Product nameAnti-AGBL4 antibody
    See all AGBL4 primary antibodies
  • Description
    Rabbit polyclonal to AGBL4
  • Specificityab74451 endogenous levels of total AGBL4 protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal sequence of human AGBL4

  • Positive control
    • HeLa, Jurkat and A549 cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab74451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 63 kDa.
ELISA 1/20000.

Target

  • FunctionMetallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
  • Sequence similaritiesBelongs to the peptidase M14 family.
  • Cellular localizationCytoplasm > cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGBL4 antibody
    • ATP/GTP binding protein like 4 antibody
    • ATP/GTP-binding protein-like 4 antibody
    • CBPC6_HUMAN antibody
    • CCP6 antibody
    • Cytosolic carboxypeptidase 6 antibody
    • FLJ14442 antibody
    see all

Anti-AGBL4 antibody images

  • All lanes : Anti-AGBL4 antibody (ab74451) at 1/500 dilution

    Lane 1 : HeLa cell extracts
    Lane 2 : Jurkat cell extracts
    Lane 3 : A549 cell extracts
    Lane 4 : A549 cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 63 kDa
    Observed band size : 63 kDa

References for Anti-AGBL4 antibody (ab74451)

This product has been referenced in:
  • Rodríguez de la Vega Otazo M  et al. Functional segregation and emerging role of cilia-related cytosolic carboxypeptidases (CCPs). FASEB J : (2012). Read more (PubMed: 23085998) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"