FunctionRequired for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Tissue specificityUbiquitously expressed.
Sequence similaritiesContains 1 Arf-GAP domain.
DomainContains FG repeats. The FG repeat region is required for acting as a cofactor of HIV-1 Rev.
Arf-GAP domain and FG repeats-containing protein 1 antibody
ArfGAP with FG repeats 1 antibody
HIV 1 Rev binding protein antibody
HIV-1 Rev-binding protein antibody
Nucleoporin like protein RIP antibody
Nucleoporin-like protein RIP antibody
Rev interacting protein antibody
Rev-interacting protein antibody
Rev/Rex activation domain-binding protein antibody
Anti-AGFG1 antibody images
Western blot - AGFG1 antibody (ab86349)
All lanes : Anti-AGFG1 antibody (ab86349) at 0.04 µg/ml
Lane 1 : HeLa whole cell lysate at 50 µg Lane 2 : HeLa whole cell lysate at 15 µg Lane 3 : HeLa whole cell lysate at 5 µg Lane 4 : 293T whole cell lysate at 50 µg
Predicted band size : 58 kDa
Exposure time : 10 seconds
Immunoprecipitation - AGFG1 antibody (ab86349)
Detection of AGFG1 by Western Blot of Immunprecipitate.
ab86349 at 1µg/ml staining AGFG1 in HeLa whole cell lysate immunoprecipitated using ab86349 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 3 seconds.
References for Anti-AGFG1 antibody (ab86349)
has not yet been referenced specifically in any publications.
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