Overview

  • Product name
    Anti-AGL antibody - C-terminal
    See all AGL primary antibodies
  • Description
    Rabbit polyclonal to AGL - C-terminal
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the C-terminal region of human AGL conjugated to KLH

  • Positive control
    • Human brain, kidney, heart, liver and muscle lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab71423 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 175 kDa (predicted molecular weight: 175 kDa).

Target

  • Function
    Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
  • Tissue specificity
    Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle.
  • Involvement in disease
    Glycogen storage disease 3
  • Sequence similarities
    Belongs to the glycogen debranching enzyme family.
  • Post-translational
    modifications
    The N-terminus is blocked.
    Ubiquitinated.
  • Cellular localization
    Cytoplasm. Under glycogenolytic conditions localizes to the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110061O17Rik antibody
    • 4-1 antibody
    • 4-glucantransferase antibody
    • 6-glucosidase antibody
    • 9430004C13Rik antibody
    • 9630046L06Rik antibody
    • AGL antibody
    • AI850929 antibody
    • Amylo 1 6 glucosidase 4 alpha glucanotransferase antibody
    • Amylo-1 antibody
    • Amylo-alpha-1 antibody
    • C77197 antibody
    • Dextrin 6-alpha-D-glucosidase antibody
    • GDE antibody
    • GDE_HUMAN antibody
    • Glycogen debrancher antibody
    • Glycogen debranching enzyme antibody
    • Glycogen storage disease type III antibody
    • Oligo-1 antibody
    see all

Images

  • All lanes : Anti-AGL antibody - C-terminal (ab71423) at 1/500 dilution

    Lane 1 : Human brain lysate
    Lane 2 : Human heart lysate
    Lane 3 : Human kidney lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human muscle lysate

    Lysates/proteins at 20 µg per lane.


    Predicted band size : 175 kDa
    Observed band size : 175 kDa

References

ab71423 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab71423.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up