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Product Name
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Agmatine antibody
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See all Agmatine antibodies (2)...
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Product type
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Primary antibodies
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Description
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Chicken polyclonal to Agmatine
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Immunogen
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Agmatine cross-linked to purifed fraction V bovine serum albumin with glutaraldehyde.
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Species Reactivity
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Not applicable.
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Specificity
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Fixed tissue cross-reactivity tested with known targets at recommended dilution.
No measurable glutaraldehyde-fixed tissue cross-reactivity (<1:1000) against L-alanine, gamma-aminobutyrate, L-citrulline, L-cysteine, D/L-glutamate, D/L-arginine, D/L-glutamine, glutathione, glycine, L-lysine, L-ornithine, L-serine, taurine, L-threonine, L-tryptophan, L-tyrosine.
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Tested applications
(see key)
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ICC
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC: 1/100. Excitation mapping by LM immunocytochemistry. True dilution at user dilution: 1/2000. Optimal fixation: 0.1-2.5% glutaraldehyde,1% formaldehyde using HPI (High Performance Immunocytochemistry). Minimum glutaraldehyde: 0.1% using HPI.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Signal Transduction >> Metabolism >> Drug metabolism
Neuroscience >> Neurotransmitter >> Biogenic Amines >> Other Amines
Neuroscience >> Sensory System >> somatosensory system >> Nociception
Signal Transduction >> Metabolism >> Amino Acids
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Relevance
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Agmatine, a product of arginine metabolism is an endogenous amine acting at imidazoline receptors with a putative role in nociception at the spinal level. Agmatine potentiates morphine analgesia and blocks symptoms of naloxone-precipitated morphine withdrawal in rats.
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Agmatine antibody (ab62667) |
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Raised in
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Chicken
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Clonality
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Polyclonal
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Isotype
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IgY
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Purity
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IgY fraction
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Storage buffer
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Preservative: 0.05% Thimerosal (merthiolate)
Constituents: 100mM Phosphate buffer, 1% sterilized goat serum Material safety datasheet (MSDS) for this product:
Thimerosal MSDS
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Purification notes
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IgYs were separated from other yolk proteins by serial PEG6000 extractions using a modification of the method of Polsonet al Immunological Investigations. 1985, 14, 323-327.
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Form
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Liquid
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Concentration
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3.000 mg/ml
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Storage instructions
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Store at +4°C. Do not freeze.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Agmatine antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Agmatine
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