Anti-AGR2 + AGR3 antibody [AGR3.4] (ab82399)

Overview

  • Product nameAnti-AGR2 + AGR3 antibody [AGR3.4]
  • Description
    Mouse monoclonal [AGR3.4] to AGR2 + AGR3
  • SpecificityRecognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa)
  • Tested applicationsSuitable for: IHC-P, WB, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human AGR3 protein

  • Positive control
    • T47D breast cancer cell line. For negative control, use H1299 lung carcinoma cell line. For IHC positive control, use human colon tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: 0.2% high-grade protease free BSA, PBS
  • Concentration information loading...
  • PurityProtein A purified
  • Purification notesPurified from ascites.
  • ClonalityMonoclonal
  • Clone numberAGR3.4
  • IsotypeIgG1
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab82399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 19-20 kDa.
ICC Use a concentration of 1 µg/ml.

Target

  • RelevanceAGR2 (Anterior Gradient 2), also known as AG2 (hAG2, HAG2 in human), or GOB4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • AG 2 antibody
    • AG 3 antibody
    • AG2 antibody
    • AG3 antibody
    • Anterior gradient 2 antibody
    • Anterior gradient 3 antibody
    • Anterior gradient 3 homolog antibody
    • Anterior gradient homolog 2 antibody
    • Anterior gradient homolog 3 antibody
    • Anterior gradient protein 2 homolog antibody
    • Anterior gradient protein 2 homolog precursor antibody
    • Anterior gradient protein 3 homolog antibody
    • Anterior gradient protein 3 homolog precursor antibody
    • BCMP11 antibody
    • Breast cancer membrane protein 11 antibody
    • Epididymis secretory protein Li 116 antibody
    • GOB 4 antibody
    • HAG 2 antibody
    • hAG 3 antibody
    • hAG3 antibody
    • HEL S 116 antibody
    • HPC8 antibody
    • PDIA17 antibody
    • PDIA18 antibody
    • Protein disulfide isomerase family A, member 17 antibody
    • Protein disulfide isomerase family A, member 18 antibody
    • Secreted cement gland homolog antibody
    • Secreted cement gland protein XAG 2 homolog antibody
    • XAG 2 antibody
    see all

Anti-AGR2 + AGR3 antibody [AGR3.4] images

  • All lanes : Anti-AGR2 + AGR3 antibody [AGR3.4] (ab82399) at 1 µg/ml

    Lane 1 : H1299 lung carcinoma cell line
    Lane 2 : T47D breast cancer cell line


    Predicted band size : 19-20 kDa
    Observed band size : 19-20 kDa

References for Anti-AGR2 + AGR3 antibody [AGR3.4] (ab82399)

ab82399 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"