Overview

  • Product nameAnti-AGTPBP1 antibody
    See all AGTPBP1 primary antibodies
  • Description
    Mouse monoclonal to AGTPBP1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Dog, Chimpanzee, Rhesus monkey
  • Immunogen

    Recombinant fragment: GAKFCVGLLR LKRLTSPLEY NLPSSLLDFE NDLIESSCKV TSPTTYVLDE DEPRFLEEVD YSAESNDELD IELAENVGDY EPSAQEEVLS DSELSRTYLP, corresponding to amino acids 1087-1186 of Human AGTPBP1 (NP_056054) with tag.

  • Positive control
    • HepG2 cell lysate; Recombinant tagged human AGTPBP1 fragment.

Properties

Applications

Our Abpromise guarantee covers the use of ab77426 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 138 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionMetallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
  • Sequence similaritiesBelongs to the peptidase M14 family.
  • Cellular localizationCytoplasm > cytosol. Nucleus. Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCP1 antibody
    • 1700020N17Rik antibody
    • 2310001G17Rik antibody
    • 2900054O13Rik antibody
    • 4930445M19Rik antibody
    • 5730402G09Rik antibody
    • AGTPBP 1 antibody
    • AGTPBP1 antibody
    • ATP/GTP binding protein 1 antibody
    • ATP/GTP-binding protein 1 antibody
    • BB114605 antibody
    • Carboxypeptidase tubulin antibody
    • CBPC1_HUMAN antibody
    • Cytosolic carboxypeptidase 1 antibody
    • DKFZp686M20191 antibody
    • KIAA1035 antibody
    • MGC90651 antibody
    • mKIAA1035 antibody
    • Nervous system nuclear protein induced by axotomy antibody
    • Nervous system nuclear protein induced by axotomy protein 1 homolog antibody
    • nmf243 antibody
    • NNA1 antibody
    • OTTHUMP00000021581 antibody
    • OTTHUMP00000063553 antibody
    • pcd antibody
    • Purkinje cell degeneration antibody
    • RP11-30C23.1 antibody
    • Soluble carboxypeptidase antibody
    • Tubulinyl Tyr carboxypeptidase antibody
    • Tyrosine carboxypeptidase antibody
    see all

Anti-AGTPBP1 antibody images

  • Anti-AGTPBP1 antibody (ab77426) at 1 µg/ml + Recombinant tagged human AGTPBP1 fragment at 0.2 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 138 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • Anti-AGTPBP1 antibody (ab77426) at 1 µg/ml + HepG2 cell lysate at 25 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 138 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

References for Anti-AGTPBP1 antibody (ab77426)

ab77426 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"