Recombinant
RabMAb

Anti-AGXT antibody [EPR13232-59] (ab178699)

Overview

  • Product name
    Anti-AGXT antibody [EPR13232-59]
    See all AGXT primary antibodies
  • Description
    Rabbit monoclonal [EPR13232-59] to AGXT
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment within Human AGXT aa 100-250. The exact sequence is proprietary.
    Database link: P21549

  • Positive control
    • HepG2 and Human fetal liver lysates; HepG2 cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab178699 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 40 kDa (predicted molecular weight: 43 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Tissue specificity
      Liver.
    • Involvement in disease
      Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1) [MIM:259900]; also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
    • Sequence similarities
      Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
    • Cellular localization
      Peroxisome. Mitochondrion matrix. Except in some HP1 patients where AGT is found in the mitochondrial matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • AGT antibody
      • AGT1 antibody
      • Agxt antibody
      • AGXT1 antibody
      • Alanine glyoxylate aminotransferase antibody
      • Alanine glyoxylate aminotransferase3 antibody
      • Alanine--glyoxylate aminotransferase antibody
      • EC 2.6.1.44 antibody
      • EC 2.6.1.51 antibody
      • Hepatic peroxisomal alanine glyoxylate aminotransferase antibody
      • Hepatic peroxisomal alanine:glyoxylate aminotransferase antibody
      • L alanine glyoxylate aminotransferase 1 antibody
      • MS773 antibody
      • PH1 antibody
      • Serine pyruvate aminotransferase antibody
      • Serine--pyruvate aminotransferase antibody
      • Serine--pyruvate aminotransferase, mitochondrial antibody
      • Serine:pyruvate aminotransferase antibody
      • SPAT antibody
      • SPT antibody
      • SPYA_HUMAN antibody
      • TLH6 antibody
      see all

    Images

    • All lanes : Anti-AGXT antibody [EPR13232-59] (ab178699) at 1/1000 dilution

      Lane 1 : HepG2 lysate
      Lane 2 : Human fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 43 kDa

    References

    ab178699 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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