Anti-AHSG antibody (ab112528)
Key features and details
- Rabbit polyclonal to AHSG
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-AHSG antibody
See all AHSG primary antibodies -
Description
Rabbit polyclonal to AHSG -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminal of Human Alpha 2 HS Glycoprotein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab112528 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. The detection limit for Alpha 2 HS Glycoprotein is approximately 2.5ng/lane.
under non-reducing and reducing conditions.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. The detection limit for Alpha 2 HS Glycoprotein is approximately 2.5ng/lane. under non-reducing and reducing conditions. |
Target
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Function
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. -
Tissue specificity
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. -
Sequence similarities
Belongs to the fetuin family.
Contains 2 cystatin fetuin-A-type domains. -
Post-translational
modificationsPhosphorylation sites are present in the extracelllular medium. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 197 Human
- Entrez Gene: 11625 Mouse
- Entrez Gene: 25373 Rat
- Omim: 138680 Human
- SwissProt: P02765 Human
- SwissProt: P29699 Mouse
- SwissProt: P24090 Rat
- Unigene: 324746 Human
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Alternative names
- 59 kDa bone sialic acid-containing protein antibody
- A2HS antibody
- Aa2-066 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab112528 has been referenced in 5 publications.
- Zhao P et al. Fetuin-A alleviates neuroinflammation against traumatic brain injury-induced microglial necroptosis by regulating Nrf-2/HO-1 pathway. J Neuroinflammation 19:269 (2022). PubMed: 36333786
- Villar M et al. Tick and Host Derived Compounds Detected in the Cement Complex Substance. Biomolecules 10:N/A (2020). PubMed: 32260542
- Yan F et al. Proteomic analysis of underlying apoptosis mechanisms of human retinal pigment epithelial ARPE-19 cells in response to mechanical stretch. J Cell Physiol 235:7604-7619 (2020). PubMed: 32437028
- Kanno T et al. A novel function of N-linked glycoproteins, alpha-2-HS-glycoprotein and hemopexin: Implications for small molecule compound-mediated neuroprotection. PLoS One 12:e0186227 (2017). PubMed: 29016670
- Majek P et al. Plasma Protein Biomarker Candidates for Myelodysplastic Syndrome Subgroups. Biomed Res Int 2015:209745 (2015). PubMed: 26448929