Overview

  • Product name
  • Description
    Rabbit polyclonal to AIFM3
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to 16 amino acids from near the amino terminus of human AIFM3 (Q96NN9).

  • Positive control
    • AIFM3 mouse tissue lysates and human brain tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 1X PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106359 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.

Target

  • Function
    Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
  • Tissue specificity
    Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
  • Sequence similarities
    Belongs to the FAD-dependent oxidoreductase family.
    Contains 1 Rieske domain.
  • Domain
    The Rieske domain induces apoptosis.
  • Cellular localization
    Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • AIFL antibody
    • Aifm3 antibody
    • AIFM3_HUMAN antibody
    • Apoptosis inducing factor 3 antibody
    • Apoptosis inducing factor like antibody
    • Apoptosis inducing factor like protein antibody
    • Apoptosis inducing factor, mitochondrion associated antibody
    • Apoptosis-inducing factor 3 antibody
    • Apoptosis-inducing factor-like protein antibody
    • FLJ30473 antibody
    • FLJ45137 antibody
    see all

Anti-AIFM3 antibody images

  • Immunofluorescence of AIFM3 in Human brain tissue with ab106359 at 20 ug/mL.

  • Lane 1 : Anti-AIFM3 antibody (ab106359) at 1 µg/ml
    Lane 2 : Anti-AIFM3 antibody (ab106359) at 2 µg/ml

    Lane 1 : Mouse brain tissue lysate
    Lane 2 : Mouse brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 67 kDa
  • Immunohistochemical staining of human brain tissue using ab106359 at 2.5 µg

References for Anti-AIFM3 antibody (ab106359)

ab106359 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106359.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up