Overview

  • Product name
  • Description
    Rabbit polyclonal to AIFM3
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to 16 amino acids from near the amino terminus of human AIFM3 (Q96NN9).

  • Positive control
    • AIFM3 mouse tissue lysates and human brain tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 1X PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106359 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.

Target

  • Function
    Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
  • Tissue specificity
    Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
  • Sequence similarities
    Belongs to the FAD-dependent oxidoreductase family.
    Contains 1 Rieske domain.
  • Domain
    The Rieske domain induces apoptosis.
  • Cellular localization
    Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • AIFL antibody
    • Aifm3 antibody
    • AIFM3_HUMAN antibody
    • Apoptosis inducing factor 3 antibody
    • Apoptosis inducing factor like antibody
    • Apoptosis inducing factor like protein antibody
    • Apoptosis inducing factor, mitochondrion associated antibody
    • Apoptosis-inducing factor 3 antibody
    • Apoptosis-inducing factor-like protein antibody
    • FLJ30473 antibody
    • FLJ45137 antibody
    see all

Images

  • Immunofluorescence of AIFM3 in Human brain tissue with ab106359 at 20 ug/mL.

  • Lane 1 : Anti-AIFM3 antibody (ab106359) at 1 µg/ml
    Lane 2 : Anti-AIFM3 antibody (ab106359) at 2 µg/ml

    Lane 1 : Mouse brain tissue lysate
    Lane 2 : Mouse brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 67 kDa
  • Immunohistochemical staining of human brain tissue using ab106359 at 2.5 µg

References

ab106359 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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