This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris-saline. pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

  • Application notes
    ELISA:Peptide ELISA: antibody detection limit dilution >1/32000.
    Western Blot: No signal obtained yet but a preliminary experiment showed low background in Human Brain extract at up to 1µg/ml.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation.
    • Tissue specificity
      Specifically expressed in brain.
    • Sequence similarities
      Belongs to the MAGUK family.
      Contains 1 guanylate kinase-like domain.
      Contains 6 PDZ (DHR) domains.
      Contains 2 WW domains.
    • Cellular localization
      Cell junction > synapse > synaptosome. Cell membrane. Membrane-associated in synaptosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • Activin receptor interacting protein 1 antibody
      • Acvri1 antibody
      • Acvrinp1 antibody
      • ACVRIP1 antibody
      • AIP 1 antibody
      • Aip-1 antibody
      • ARIP1 antibody
      • Atrophin 1 interacting protein 1 antibody
      • Atrophin 1 interacting protein A antibody
      • Atrophin-1-interacting protein 1 antibody
      • Atrophin-1-interacting protein A antibody
      • KIAA0705 antibody
      • MAGI-2 antibody
      • MAGI2 antibody
      • MAGI2_HUMAN antibody
      • Membrane associated guanylate kinase 2 antibody
      • Membrane associated guanylate kinase inverted 2 antibody
      • Membrane associated guanylate kinase WW and PDZ domain containing 2 antibody
      • Membrane associated guanylate kinase WW and PDZ domain containing protein 2 antibody
      • Membrane-associated guanylate kinase antibody
      • Membrane-associated guanylate kinase inverted 2 antibody
      • S SCAM antibody
      • SSCAM antibody
      • WW and PDZ domain-containing protein 2 antibody
      see all

    References

    This product has been referenced in:
    • Lau AC  et al. An H4K16 histone acetyltransferase mediates decondensation of the X chromosome in C. elegans males. Epigenetics Chromatin 9:44 (2016). WB . Read more (PubMed: 27777629) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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