Overview

  • Product nameAnti-AIPL1 antibody
    See all AIPL1 primary antibodies
  • Description
    Rabbit polyclonal to AIPL1
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A 17 amino acid synthetic peptide corresponding to a region within the C terminus of the Human AIPL1

  • Positive control
    • Human Adrenal tissue and Human brain lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab111996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionMay be important in protein trafficking and/or protein folding and stabilization.
  • Tissue specificityHighly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.
  • Involvement in diseaseDefects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4) [MIM:604393]. LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
  • Sequence similaritiesContains 1 PPIase FKBP-type domain.
    Contains 3 TPR repeats.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • A930007I01Rik antibody
    • Aipl1 antibody
    • AIPL1_HUMAN antibody
    • AIPL2 antibody
    • Aryl hydrocarbon interacting protein like 1 antibody
    • Aryl hydrocarbon receptor interacting protein like 1 antibody
    • Aryl-hydrocarbon-interacting protein-like 1 antibody
    • LCA4 antibody
    • MGC25485 antibody
    • OTTHUMP00000128207 antibody
    • OTTMUSP00000006382 antibody
    • RP23-401C17.1 antibody
    see all

Anti-AIPL1 antibody images

  • ab111996 at 5 µg/ml staining AIPL1 in Formalin-Fixed, Paraffin-Embedded Human Adrenal tissue by Immunohistochemistry
  • Lane 1 : Anti-AIPL1 antibody (ab111996) at 1 µg/ml
    Lane 2 : Anti-AIPL1 antibody (ab111996) at 2 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate


    Predicted band size : 44 kDa

References for Anti-AIPL1 antibody (ab111996)

ab111996 has not yet been referenced specifically in any publications.

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