Overview

  • Product nameAnti-Ajuba antibody
    See all Ajuba primary antibodies
  • Description
    Mouse polyclonal to Ajuba
  • SpecificityThis antibody is reactive against mammalian transfected lysate.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Ajuba protein (Human)

  • Positive control
    • Ajuba transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67666 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).
    Detection Antibody Pair.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceAjuba is a member of LIM domain containing proteins that contribute to cell fate determination and regulate cell proliferation and differentiation. Ajuba is also involved in the regulation of actin cytoskeleton dynamics and cell migration. Ajuba plays a important role in the regulation of the kinase activity of AURKA/Aurora A for mitotic commitment. Is also a component of the IL 1 signaling pathway modulating IL 1 induced NF kappa B activation by influencing the assembly and activity of the PRKCZ/SQSTM1/TRAF6 multiprotein signaling complex. Ajuba is also a negative regulator of the Wnt signaling pathway.
    • Cellular localizationCytoplasm, cytoskeleton. Cell membrane. Cell junction. Nucleus. Centrosome. Note: Shuttles between the cytoplasm and the nucleus.
    • Database links
    • Alternative names
      • Ajuba LIM protein antibody
      • Ajuba, mouse, homolog of antibody
      • Jub ajuba homolog antibody
      • Jub antibody
      • LIM domain containing protein ajuba antibody
      • MGC15563 antibody
      • Protein ajuba antibody
      see all

    Anti-Ajuba antibody images

    • All lanes : Anti-Ajuba antibody (ab67666) at 1/500 dilution

      Lane 1 : Ajuba transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 57 kDa
      Observed band size : 57 kDa

    References for Anti-Ajuba antibody (ab67666)

    ab67666 has not yet been referenced specifically in any publications.

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    Leider haben wir keinerlei Erfahrungsberichte über ein mögliches dominantes Epitop das im C-terminalen Drittel des Proteins Ajuba liegt und einen Hinweis geben würde, dass die Deletionsmutante...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"