• Product nameAnti-AKAP13 antibody
    See all AKAP13 primary antibodies
  • Description
    Mouse monoclonal to AKAP13
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 1-111 of Human AKAP13



Our Abpromise guarantee covers the use of ab56916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAnchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element-specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Isoform 6 stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
    • Tissue specificityIsoform 3 and isoform 6 are found in hematopoietic cells, skeletal muscle, lung, heart, estrogen-responsive reproductive tissues, including breast ductal epithelium. Also found in testis and breast cancer cell lines. Isoform 6 is not found in brain, placenta, liver, pancreas or kidney. Isoform 7 is expressed in myeloid and lymphoid lineages, a variety of epithelial tissues and skeletal muscle. Isoform 2 is predominantly found in the heart and at lower levels in the lung, placenta, kidney, pancreas, skeletal muscle and liver.
    • Sequence similaritiesContains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
    • DomainBoth the DH and PH domains are required for transforming activity.
    • Cellular localizationCytoplasm; Cytoplasm. Nucleus and Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • A kinase (PRKA) anchor protein 13 antibody
      • A kinase anchor protein 13 antibody
      • A kinase anchoring protein antibody
      • A-kinase anchor protein 13 antibody
      • AKAP 13 antibody
      • AKAP Lbc antibody
      • AKAP-13 antibody
      • AKAP-Lbc antibody
      • AKAP13 antibody
      • AKP13_HUMAN antibody
      • ARHGEF13 antibody
      • Breast cancer nuclear receptor binding auxiliary protein antibody
      • Breast cancer nuclear receptor-binding auxiliary protein antibody
      • BRX antibody
      • c lbc antibody
      • FLJ11952 antibody
      • FLJ43341 antibody
      • Guanine nucleotide exchange factor Lbc antibody
      • HA 3 antibody
      • HA3 antibody
      • Ht 31 antibody
      • Ht31 antibody
      • Human thyroid anchoring protein 31 antibody
      • Human thyroid-anchoring protein 31 antibody
      • LBC antibody
      • LBC oncogene antibody
      • Lymphoid blast crisis oncogene antibody
      • Non oncogenic Rho GTPase specific GTP exchange factor antibody
      • Non-oncogenic Rho GTPase-specific GTP exchange factor antibody
      • p47 antibody
      • Protein kinase A anchoring protein 13 antibody
      • Protein kinase A-anchoring protein 13 antibody
      • PROTO LB antibody
      • PROTO LBC antibody
      see all

    Anti-AKAP13 antibody images

    • Anti-AKAP13 antibody (ab56916) at 5 µg/ml + 0.2 µg/lane of partial recombinant AKAP13 protein with a tag

      Goat anti mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

      Predicted band size : 308 kDa
      Observed band size : 38 kDa (why is the actual band size different from the predicted?)

    References for Anti-AKAP13 antibody (ab56916)

    ab56916 has not yet been referenced specifically in any publications.

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