Overview

  • Product name
  • Description
    Rabbit polyclonal to AKAP8
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein expressed in E. Coli (Mouse)

  • Positive control
    • WB: human A431 lysates and HeLa nuclear extract. ICC: human A431 cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: 0.1M Tris glycine. pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab32822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 95 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function
    Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).
  • Tissue specificity
    Highly expressed in heart, liver, skeletal muscle, kidney and pancreas.
  • Sequence similarities
    Belongs to the AKAP95 family.
    Contains 2 C2H2 AKAP95-type zinc fingers.
  • Cellular localization
    Nucleus matrix. Associated with the nuclear matrix. Redistributed and detached from condensed chromatin during mitosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • A kinase (PRKA) anchor protein 8 antibody
    • A kinase anchor protein 8 antibody
    • A kinase anchor protein 95 antibody
    • A kinase anchor protein 95 kDa antibody
    • A kinase anchor protein 95kDa antibody
    • A-kinase anchor protein 8 antibody
    • A-kinase anchor protein 95 kDa antibody
    • AKAP 8 antibody
    • AKAP 95 antibody
    • AKAP-8 antibody
    • AKAP-95 antibody
    • Akap8 antibody
    • AKAP8_HUMAN antibody
    • AKAP95 antibody
    • DKFZp586B1222 antibody
    see all

References

This product has been referenced in:
  • Plasman K  et al. Probing the efficiency of proteolytic events by positional proteomics. Mol Cell Proteomics 10:M110.003301 (2011). WB ; Human . Read more (PubMed: 21048194) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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