The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
FunctionActs as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Tissue specificityFound in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Sequence similaritiesBelongs to the aldo/keto reductase family.
Cellular localizationLysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.