Overview

  • Product name
    Anti-AKR1D1 antibody
  • Description
    Rabbit polyclonal to AKR1D1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rabbit
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 184 and 322 of AKR1D1 (AAI30626).

  • Positive control
    • A549 whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab101393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 37 kDa.

Target

  • Function
    Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
  • Tissue specificity
    Highly expressed in liver. Expressed in testis and weakly in colon.
  • Involvement in disease
    Congenital bile acid synthesis defect 2
  • Sequence similarities
    Belongs to the aldo/keto reductase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3-oxo-5-beta-steroid 4-dehydrogenase antibody
    • 3o5bred antibody
    • AK1D1_HUMAN antibody
    • AKR1D1 antibody
    • aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody
    • Aldo keto reductase family 1 member D1 antibody
    • Aldo-keto reductase family 1 member D1 antibody
    • CBAS2 antibody
    • Delta(4) 3 ketosteroid 5 beta reductase antibody
    • Delta(4) 3 oxosteroid 5 beta reductase antibody
    • Delta(4)-3-ketosteroid 5-beta-reductase antibody
    • Delta(4)-3-oxosteroid 5-beta-reductase antibody
    • SRD5B1 antibody
    • steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody
    • steroid 5 beta reductase antibody
    see all

Images

  • Anti-AKR1D1 antibody (ab101393) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size : 37 kDa

References

ab101393 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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