Overview

  • Product nameAnti-AKR1D1 antibody
    See all AKR1D1 primary antibodies
  • Description
    Mouse monoclonal to AKR1D1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: NPIWVNVSSP PLLKDALLNS LGKRYNKTAA QIVLRFNIQR GVVVIPKSFN LERIKENFQI FDFSLTEEEM KDIEALNKNV RFVELLMWRD HPEYPFHDEY , corresponding to amino acids 227-327 of Human AKR1D1

Properties

Applications

Our Abpromise guarantee covers the use of ab57993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionEfficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
    • Tissue specificityHighly expressed in liver. Expressed in testis and weakly in colon.
    • Involvement in diseaseCongenital bile acid synthesis defect 2
    • Sequence similaritiesBelongs to the aldo/keto reductase family.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • 3-oxo-5-beta-steroid 4-dehydrogenase antibody
      • 3o5bred antibody
      • AK1D1_HUMAN antibody
      • AKR1D1 antibody
      • aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody
      • Aldo keto reductase family 1 member D1 antibody
      • Aldo-keto reductase family 1 member D1 antibody
      • CBAS2 antibody
      • Delta(4) 3 ketosteroid 5 beta reductase antibody
      • Delta(4) 3 oxosteroid 5 beta reductase antibody
      • Delta(4)-3-ketosteroid 5-beta-reductase antibody
      • Delta(4)-3-oxosteroid 5-beta-reductase antibody
      • SRD5B1 antibody
      • steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody
      • steroid 5 beta reductase antibody
      see all

    Anti-AKR1D1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57993 AKR1D1 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    References for Anti-AKR1D1 antibody (ab57993)

    ab57993 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57993.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"