Overview

  • Product nameAnti-AKR1D1 antibody
    See all AKR1D1 primary antibodies
  • Description
    Mouse polyclonal to AKR1D1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human AKR1D1 (NP_005980.1)

  • Positive control
    • Human liver lysate AKR1D1 Transfected 293T lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab89166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 37 kDa.

Target

  • FunctionEfficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
  • Tissue specificityHighly expressed in liver. Expressed in testis and weakly in colon.
  • Involvement in diseaseCongenital bile acid synthesis defect 2
  • Sequence similaritiesBelongs to the aldo/keto reductase family.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3-oxo-5-beta-steroid 4-dehydrogenase antibody
    • 3o5bred antibody
    • AK1D1_HUMAN antibody
    • AKR1D1 antibody
    • aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody
    • Aldo keto reductase family 1 member D1 antibody
    • Aldo-keto reductase family 1 member D1 antibody
    • CBAS2 antibody
    • Delta(4) 3 ketosteroid 5 beta reductase antibody
    • Delta(4) 3 oxosteroid 5 beta reductase antibody
    • Delta(4)-3-ketosteroid 5-beta-reductase antibody
    • Delta(4)-3-oxosteroid 5-beta-reductase antibody
    • SRD5B1 antibody
    • steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody
    • steroid 5 beta reductase antibody
    see all

Anti-AKR1D1 antibody images

  • Anti-AKR1D1 antibody (ab89166) at 1/500 dilution + Human liver lysate at 50 µg

    Predicted band size : 37 kDa
  • All lanes : Anti-AKR1D1 antibody (ab89166) at 1/500 dilution

    Lane 1 : Transfected 293T lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 37 kDa

References for Anti-AKR1D1 antibody (ab89166)

ab89166 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89166.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"