• Product nameAnti-ALAD antibody
    See all ALAD primary antibodies
  • Description
    Mouse polyclonal to ALAD
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human ALAD, amino acids 1-339 (NP_000022.2)

  • Positive control
    • Human liver tissue lysate, ALAD transfected 293T cell lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab88875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa.


  • FunctionCatalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
  • PathwayPorphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.
  • Involvement in diseaseDefects in ALAD are the cause of acute hepatic porphyria (AHP) [MIM:612740]. AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.
  • Sequence similaritiesBelongs to the ALADH family.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALAD antibody
    • ALADH antibody
    • ALADR antibody
    • Aminolevulinate dehydratase antibody
    • Aminolevulinate, delta, dehydratase antibody
    • Delta aminolevulinic acid dehydratase antibody
    • Delta-aminolevulinic acid dehydratase antibody
    • HEM2_HUMAN antibody
    • Lv antibody
    • MGC5057 antibody
    • OTTMUSP00000009376 antibody
    • OTTMUSP00000009377 antibody
    • PBGS antibody
    • Porphobilinogen synthase antibody
    • RP11-10I9.1 antibody
    • RP24-189G18.9 antibody
    see all

Anti-ALAD antibody images

  • Anti-ALAD antibody (ab88875) at 1 µg/ml + human liver tissue lysate at 50 µg

    Predicted band size : 37 kDa
    Observed band size : 37 kDa
    Additional bands at : 20 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-ALAD antibody (ab88875) at 1 µg/ml

    Lane 1 : ALAD transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 37 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

References for Anti-ALAD antibody (ab88875)

ab88875 has not yet been referenced specifically in any publications.

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