Recombinant
RabMAb

Anti-Albumin antibody [EPR12780(B)] (ab175934)

Overview

  • Product name
    Anti-Albumin antibody [EPR12780(B)]
    See all Albumin primary antibodies
  • Description
    Rabbit monoclonal [EPR12780(B)] to Albumin
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Cow, Human
  • Immunogen

    Synthetic peptide within Cow Albumin aa 500-600 (Cysteine residue). The exact sequence is proprietary.
    Database link: P02769

  • Positive control
    • HepG2, Hela, human plasma, human serum lysates
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab175934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 69 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function
      Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
    • Tissue specificity
      Plasma.
    • Involvement in disease
      Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
    • Sequence similarities
      Belongs to the ALB/AFP/VDB family.
      Contains 3 albumin domains.
    • Post-translational
      modifications
      Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
      Glycated in diabetic patients.
      Phosphorylation sites are present in the extracelllular medium.
      Acetylated on Lys-223 by acetylsalicylic acid.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Form
      There are 2 isoforms produced by alternative splicing.
    • Alternative names
      • alb antibody
      • ALBU_HUMAN antibody
      • Albumin (32 AA) antibody
      • Albumin (AA 34) antibody
      • cell growth inhibiting protein 42 antibody
      • DKFZp779N1935 antibody
      • GIG20 antibody
      • GIG42 antibody
      • growth-inhibiting protein 20 antibody
      • OTTHUMP00000220436 antibody
      • OTTHUMP00000220438 antibody
      • OTTHUMP00000220439 antibody
      • PRO0883 antibody
      • PRO0903 antibody
      • PRO1341 antibody
      • PRO1708 antibody
      • PRO2044 antibody
      • PRO2619 antibody
      • PRO2675 antibody
      • Serum albumin antibody
      • UNQ696/PRO1341 antibody
      see all

    Images

    • All lanes : Anti-Albumin antibody [EPR12780(B)] (ab175934) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : Hela cell lysate
      Lane 3 : Human plasma lysate
      Lane 4 : Human serum lysate
      Lane 5 : Bovine serum albumin lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 69 kDa

    References

    ab175934 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab175934.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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