Anti-Aldehyde dehydrogenase 10 antibody (ab183668)

Overview

  • Product name
    Anti-Aldehyde dehydrogenase 10 antibody
    See all Aldehyde dehydrogenase 10 primary antibodies
  • Description
    Rabbit polyclonal to Aldehyde dehydrogenase 10
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment within Human Aldehyde dehydrogenase 10 aa 158-442. The exact sequence is proprietary.
    Database link: P51648

  • Positive control
    • HeLa whole cell and HeLa membrane lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab183668 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 55 kDa.

Target

  • Function
    Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length.
  • Involvement in disease
    Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS) [MIM:270200]. SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects.
  • Sequence similarities
    Belongs to the aldehyde dehydrogenase family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ahd 3 antibody
    • Ahd 3r antibody
    • Ahd3 antibody
    • Ahd3 r antibody
    • AL3A2_HUMAN antibody
    • Aldehyde dehydrogenase 10 antibody
    • Aldehyde dehydrogenase 3 antibody
    • Aldehyde dehydrogenase 3 family, member A2 antibody
    • Aldehyde dehydrogenase family 3 member A2 antibody
    • Aldehyde dehydrogenase family 3, subfamily A2 antibody
    • Aldehyde dehydrogenase, family 3, subfamily A, member 2 antibody
    • ALDH10 antibody
    • Aldh3 antibody
    • ALDH3A2 antibody
    • Aldh4 antibody
    • Aldh4 r antibody
    • Aldh4r antibody
    • DKFZp686E23276 antibody
    • FALDH antibody
    • Fatty aldehyde dehydrogenase antibody
    • FLJ20851 antibody
    • Microsomal aldehyde dehydrogenase antibody
    • msALDH antibody
    • SLS antibody
    see all

Images

  • All lanes : Anti-Aldehyde dehydrogenase 10 antibody (ab183668) at 1/3000 dilution

    Lane 1 : HeLa whole cell lysate
    Lane 2 : HeLa membrane lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 55 kDa

    7.5% SDS-PAGE

References

ab183668 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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