Anti-ALDH1A1 antibody [EP1933Y] (ab52492)

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ab52492 has been referenced in 62 publications.

  • Boulding T  et al. LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer. Sci Rep 8:73 (2018). PubMed: 29311580
  • Yamauchi T  et al. Dynamic changes in CD44v-positive cells after preoperative anti-HER2 therapy and its correlation with pathologic complete response in HER2-positive breast cancer. Oncotarget 9:6872-6882 (2018). PubMed: 29467936
  • Fu Z  et al. LncRNA HOTTIP modulates cancer stem cell properties in human pancreatic cancer by regulating HOXA9. Cancer Lett 410:68-81 (2017). ICC/IF . PubMed: 28947139
  • Wang H  et al. CD44+/CD24-phenotype predicts a poor prognosis in triple-negative breast cancer. Oncol Lett 14:5890-5898 (2017). PubMed: 29113223
  • Duong HQ  et al. Silencing of NRF2 Reduces the Expression of ALDH1A1 and ALDH3A1 and Sensitizes to 5-FU in Pancreatic Cancer Cells. Antioxidants (Basel) 6:N/A (2017). PubMed: 28671577
  • Dong Y  et al. Aldehyde dehydrogenase 1 isoenzyme expression as a marker of cancer stem cells correlates to histopathological features in head and neck cancer: A meta-analysis. PLoS One 12:e0187615 (2017). PubMed: 29112953
  • Jiang X  et al. Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis. Mol Med Rep 15:1123-1134 (2017). PubMed: 28112378
  • Daniels BP  et al. Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection. J Clin Invest 127:843-856 (2017). PubMed: 28134626
  • Morrice N  et al. Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice. Sci Rep 7:43782 (2017). PubMed: 28256636
  • Tian C  et al. ABCG1 as a potential oncogene in lung cancer. Exp Ther Med 13:3189-3194 (2017). PubMed: 28588672
  • Yu J  et al. TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1. Oncotarget 8:38426-38443 (2017). WB, IHC-P ; Mouse, Human . PubMed: 28415606
  • Wang W  et al. MiR-23b controls ALDH1A1 expression in cervical cancer stem cells. BMC Cancer 17:292 (2017). WB ; Human . PubMed: 28449663
  • Saunders JH  et al. Individual patient oesophageal cancer 3D models for tailored treatment. Oncotarget 8:24224-24236 (2017). IHC-P ; Human . PubMed: 27736801
  • Wu B  et al. Reconstructing Lineage Hierarchies of Mouse Uterus Epithelial Development Using Single-Cell Analysis. Stem Cell Reports 9:381-396 (2017). IHC-P ; Mouse . PubMed: 28625536
  • Kim JY  et al. CWP232228 targets liver cancer stem cells through Wnt/ß-catenin signaling: a novel therapeutic approach for liver cancer treatment. Oncotarget 7:20395-409 (2016). IF . PubMed: 26967248
  • Boyle SE  et al. CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity. Cancer Res 76:3965-77 (2016). IHC-P ; Human . PubMed: 27325642
  • Yang F  et al. Evaluation of Breast Cancer Stem Cells and Intratumor Stemness Heterogeneity in Triple-negative Breast Cancer as Prognostic Factors. Int J Biol Sci 12:1568-1577 (2016). PubMed: 27994520
  • Ishiguro T  et al. Establishment and Characterization of an In Vitro Model of Ovarian Cancer Stem-like Cells with an Enhanced Proliferative Capacity. Cancer Res 76:150-60 (2016). PubMed: 26669863
  • Hanssen A  et al. Characterization of different CTC subpopulations in non-small cell lung cancer. Sci Rep 6:28010 (2016). PubMed: 27302574
  • Lv X  et al. Association between ALDH1+/CD133+ stem-like cells and tumor angiogenesis in invasive ductal breast carcinoma. Oncol Lett 11:1750-1756 (2016). IHC . PubMed: 26998072
  • Sato K  et al. Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression. PLoS One 11:e0154186 (2016). IHC . PubMed: 27100677
  • Braun F  et al. Altered lipid metabolism in the aging kidney identified by three layered omic analysis. Aging (Albany NY) 8:441-57 (2016). IHC . PubMed: 26886165
  • Ma Y  et al. Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer. Int J Oncol 48:2349-58 (2016). PubMed: 27035162
  • Rodriguez-Torres M & Allan AL Aldehyde dehydrogenase as a marker and functional mediator of metastasis in solid tumors. Clin Exp Metastasis 33:97-113 (2016). PubMed: 26445849
  • Matsumoto T  et al. Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism. PLoS One 11:e0162049 (2016). IHC-P . PubMed: 27564706
  • Yu J  et al. High-throughput proteomics integrated with gene microarray for discovery of colorectal cancer potential biomarkers. Oncotarget 7:75279-75292 (2016). IHC-P ; Human . PubMed: 27661117
  • Collina F  et al. Prognostic Value of Cancer Stem Cells Markers in Triple-Negative Breast Cancer. Biomed Res Int 2015:158682 (2015). IHC . PubMed: 26504780
  • Lee H  et al. Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis. EMBO Mol Med 7:819-30 (2015). WB . PubMed: 25864124
  • Papaconstantinou J  et al. Attenuation of p38a MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells. Aging (Albany NY) 7:718-33 (2015). IHC-P ; Mouse . PubMed: 26423835
  • Leinung M  et al. Expression of ALDH1A1 and CD44 in primary head and neck squamous cell carcinoma and their value for carcinogenesis, tumor progression and cancer stem cell identification. Oncol Lett 10:2289-2294 (2015). PubMed: 26622836
  • Kim T  et al. A basal-like breast cancer-specific role for SRF-IL6 in YAP-induced cancer stemness. Nat Commun 6:10186 (2015). PubMed: 26671411
  • Zhang S  et al. Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer. Oncogene N/A:N/A (2015). PubMed: 26279302
  • Foster JW  et al. Low-glucose enhances keratocyte-characteristic phenotype from corneal stromal cells in serum-free conditions. Sci Rep 5:10839 (2015). ICC/IF ; Human . PubMed: 26039975
  • Chen Z  et al. Stem cell protein Piwil1 endowed endometrial cancer cells with stem-like properties via inducing epithelial-mesenchymal transition. BMC Cancer 15:811 (2015). IHC . PubMed: 26506848
  • Sloniecka M  et al. Expression Profiles of Neuropeptides, Neurotransmitters, and Their Receptors in Human Keratocytes In Vitro and In Situ. PLoS One 10:e0134157 (2015). WB ; Human . PubMed: 26214847
  • Zhang S  et al. Tumor-suppressive activity of Lunatic Fringe in prostate through differential modulation of Notch receptor activation. Neoplasia 16:158-67 (2014). IHC-P ; Mouse . PubMed: 24709423
  • Ito K  et al. Inflammation rapidly modulates the expression of ALDH1A1 (RALDH1) and vimentin in the liver and hepatic macrophages of rats in vivo. Nutr Metab (Lond) 11:54 (2014). PubMed: 25926859
  • Condello S  et al. ß-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroids. Oncogene N/A:N/A (2014). PubMed: 24954508
  • Domanskyi A  et al. Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance. Front Cell Neurosci 8:275 (2014). IHC-P ; Mouse . PubMed: 25249938
  • Li XS  et al. ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer. BMC Cancer 14:705 (2014). IHC-P ; Human . PubMed: 25253129
  • Mizukami T  et al. Immunohistochemical analysis of cancer stem cell markers in pancreatic adenocarcinoma patients after neoadjuvant chemoradiotherapy. BMC Cancer 14:687 (2014). IHC-P ; Human . PubMed: 25240521
  • Ferrand N  et al. Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype. PLoS One 9:e87878 (2014). WB ; Human . PubMed: 24498388
  • DA Cruz Paula A  et al. Co-expression of stem cell markers ALDH1 and CD44 in non-malignant and neoplastic lesions of the breast. Anticancer Res 34:1427-34 (2014). IHC-P ; Human . PubMed: 24596390
  • Larrayoz M  et al. Contrasting responses of non-small cell lung cancer to antiangiogenic therapies depend on histological subtype. EMBO Mol Med 6:539-50 (2014). IHC-P . PubMed: 24500694
  • Goossens-Beumer IJ  et al. Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer. Br J Cancer 110:2935-44 (2014). PubMed: 24786601
  • Zhong Y  et al. Expression of ALDH1 in breast invasive ductal carcinoma: an independent predictor of early tumor relapse. Cancer Cell Int 13:60 (2013). IHC-P ; Human . PubMed: 23767668
  • Ko SB  et al. Inflammation increases cells expressing ZSCAN4 and progenitor cell markers in the adult pancreas. Am J Physiol Gastrointest Liver Physiol 304:G1103-16 (2013). PubMed: 23599043
  • Gomez-Casal R  et al. Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes. Mol Cancer 12:94 (2013). PubMed: 23947765
  • Nallamshetty S  et al. Deficiency of retinaldehyde dehydrogenase 1 induces BMP2 and increases bone mass in vivo. PLoS One 8:e71307 (2013). WB ; Mouse . PubMed: 23951127
  • Patlolla JM  et al. ß-Escin inhibits NNK-induced lung adenocarcinoma and ALDH1A1 and RhoA/Rock expression in A/J mice and growth of H460 human lung cancer cells. Cancer Prev Res (Phila) 6:1140-9 (2013). IHC ; Mouse . PubMed: 23963803
  • Noto A  et al. Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells. Cell Death Dis 4:e947 (2013). IHC-P ; Human . PubMed: 24309934
  • Kiefer FW  et al. Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue. Nat Med 18:918-25 (2012). WB ; Mouse . PubMed: 22561685
  • Koukourakis MI  et al. Cancer stem cell phenotype relates to radio-chemotherapy outcome in locally advanced squamous cell head-neck cancer. Br J Cancer 106:846-53 (2012). IHC . PubMed: 22333601
  • Khoury T  et al. Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy. Mod Pathol 25:388-97 (2012). PubMed: 22080062
  • Maddox J  et al. Transcription factor Oct1 is a somatic and cancer stem cell determinant. PLoS Genet 8:e1003048 (2012). IF . PubMed: 23144633
  • Burga LN  et al. Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice. Breast Cancer Res 13:R30 (2011). ICC/IF ; Human . PubMed: 21396117
  • Visus C  et al. Targeting ALDH(bright) human carcinoma-initiating cells with ALDH1A1-specific CD8? T cells. Clin Cancer Res 17:6174-84 (2011). PubMed: 21856769
  • Li W  et al. Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta1. J Pharmacol Exp Ther 336:87-94 (2011). WB ; Human . PubMed: 20884751
  • Gong C  et al. Markers of tumor-initiating cells predict chemoresistance in breast cancer. PLoS One 5:e15630 (2010). IHC-P ; Human . PubMed: 21187973
  • Boonyaratanakornkit JB  et al. Selection of tumorigenic melanoma cells using ALDH. J Invest Dermatol 130:2799-808 (2010). PubMed: 20739950
  • Sullivan JP  et al. Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling. Cancer Res 70:9937-9948 (2010). IHC-P ; Human . PubMed: 21118965
  • Carvalho-Oliveira IM  et al. Proteomic analysis of naphthalene-induced airway epithelial injury and repair in a cystic fibrosis mouse model. J Proteome Res 8:3606-16 (2009). PubMed: 19438287


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