• Product nameAnti-ALDH2 antibody [EPR4493]
    See all ALDH2 primary antibodies
  • Description
    Rabbit monoclonal [EPR4493] to ALDH2
  • SpecificityThe antibody immunogen has 82% homology with ALDH1B1 (P30837) and 77% with ALDH1A1 (P00352). BLAST results show for both proteins 6 aa in a row with 100% homology, therefore a cross-reactivity with these proteins is likely.
  • Tested applicationsSuitable for: WB, IP, IHC-P, ICCmore details
    Unsuitable for: Flow Cyt
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human ALDH2.

  • Positive control
    • HepG2 and A549 cell lysates; Mouse liver and rat liver lysates; Human colon tissue
  • General notes

    Alternative versions available:
    Anti-ALDH2 antibody (HRP) [EPR4493] (ab199210)

    Produced using Abcam's RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5, 675, 063 and/or 7, 429, 487.

    This product is a recombinant rabbit monoclonal antibody.


Our Abpromise guarantee covers the use of ab108306 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 56 kDa.
IP 1/10 - 1/100.
IHC-P 1/50 - 1/100. Antigen retrieval is recommended.
ICC 1/100 - 1/250.
  • Application notesIs unsuitable for Flow Cyt.
  • Target

    • PathwayAlcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.
    • Sequence similaritiesBelongs to the aldehyde dehydrogenase family.
    • Cellular localizationMitochondrion matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • Acetaldehyde dehydrogenase 2 antibody
      • Aldehyde dehydrogenase 2 family (mitochondrial) antibody
      • Aldehyde dehydrogenase 2 family antibody
      • Aldehyde dehydrogenase mitochondrial antibody
      • Aldehyde dehydrogenase, mitochondrial antibody
      • ALDH 2 antibody
      • ALDH class 2 antibody
      • ALDH E2 antibody
      • ALDH-E2 antibody
      • Aldh2 antibody
      • ALDH2_HUMAN antibody
      • ALDHI antibody
      • ALDM antibody
      • Liver mitochondrial ALDH antibody
      • MGC1806 antibody
      • Mitochondrial aldehyde dehydrogenase 2 antibody
      • MS767 antibody
      • Nucleus encoded mitochondrial aldehyde dehydrogenase 2 antibody
      see all

    Anti-ALDH2 antibody [EPR4493] images

    • ab108306 at 1/50 dilution, staining ALDH2 in paraffin-embedded Human colon tissue
    • All lanes : Anti-ALDH2 antibody [EPR4493] (ab108306) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : A549 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 56 kDa
    • All lanes : Anti-ALDH2 antibody [EPR4493] (ab108306) at 1/1000 dilution

      Lane 1 : Mouse liver lysate
      Lane 2 : Rat liver lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 56 kDa

    References for Anti-ALDH2 antibody [EPR4493] (ab108306)

    This product has been referenced in:
    • Yu YH  et al. PKC-ALDH2 Pathway Plays a Novel Role in Adipocyte Differentiation. PLoS One 11:e0161993 (2016). WB, IP ; Mouse . Read more (PubMed: 27575855) »
    • Ferrand N  et al. Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype. PLoS One 9:e87878 (2014). WB ; Human . Read more (PubMed: 24498388) »

    See all 2 Publications for this product

    Product Wall

    Thank you for contacting us.

    Your credit note ID is **

    I am sorry that this antibody did not perform as stated on the datasheet. I have asked our accounting department to issue a credit note for you, which can be redeemed against ...

    Read More

    Thank you for your enquiry and your interest in our products. Here are the answers to your questions: 1) As the datasheet indicates this antibody is tissue culture supernatant and not affinity purified. Therefore the IgG concentration ha...

    Read More