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Storage instructions Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab106819 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 57 kDa.
Function Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Tissue specificity Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
Pathway Amino-acid degradation; 4-aminobutanoate degradation.
Involvement in disease Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.
Sequence similarities Belongs to the aldehyde dehydrogenase family.
Cellular localization Mitochondrion.
Information by UniProt
Aldedehyde dehydrogenase 5 family antibody
Aldehyde dehydrogenase 5 family member A1 antibody
Aldehyde dehydrogenase 5A1 antibody
Anti-ALDH5A1 antibody images
References for Anti-ALDH5A1 antibody (ab106819)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"