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Goat polyclonal to ALDH5A1
ab106819 is expected to recognize both reported isoforms (NP_733936.1; NP_001071.1).
Mouse, Rat, Human
Predicted to work with:
Cow, Dog, Orangutan
, corresponding to internal sequence amino acids 288-299 of Human ALDH5A1 (NP_733936.1; NP_001071.1).
Human, Mouse and Rat Liver lysates.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
Immunogen affinity purified
ab106819 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 57 kDa.
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
Amino-acid degradation; 4-aminobutanoate degradation.
Involvement in disease
Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.
Belongs to the aldehyde dehydrogenase family.
Information by UniProt
Aldedehyde dehydrogenase 5 family antibody
Aldehyde dehydrogenase 5 family member A1 antibody
Aldehyde dehydrogenase 5A1 antibody
has not yet been referenced specifically in any publications.
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