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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.09% Sodium Azide
Concentration information loading...
Immunogen affinity purified
This antibody was purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 21280157
1/50 - 1/100. Detects a band of approximately 55 kDa (predicted molecular weight: 57 kDa).
1/10 - 1/50.
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
Amino-acid degradation; 4-aminobutanoate degradation.
Involvement in disease
Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.
Belongs to the aldehyde dehydrogenase family.
Information by UniProt
Aldedehyde dehydrogenase 5 family antibody
Aldehyde dehydrogenase 5 family member A1 antibody
Aldehyde dehydrogenase 5A1 antibody
Anti-ALDH5A1 antibody images
References for Anti-ALDH5A1 antibody (ab65469)
This product has been referenced in:
et al. Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells Is Primarily Due To Isoform ALDH1A3 and Its Expression Is Predictive of Metastasis. Stem Cells 29:32-45 (2011).
Read more (PubMed: 21280157) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"