Overview

  • Product nameAnti-ALDH6A1 antibody
    See all ALDH6A1 primary antibodies
  • Description
    Goat polyclonal to ALDH6A1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Dog, Pig
  • Immunogen

    Synthetic peptide:

    SNKAGEYIFER

    by a Cysteine residue linker, corresponding to internal sequence amino acids 262-272 of Human ALDH6A1 (NP_005580.1).

  • Positive control
    • Human, Mouse and Rat Kidney lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab109576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 58 kDa).

Target

  • FunctionPlays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
  • Involvement in diseaseDefects in ALDH6A1 are the cause of methylmalonate semialdehyde dehydrogenase deficiency (MMSDH deficiency) [MIM:603178]. This is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
  • Sequence similaritiesBelongs to the aldehyde dehydrogenase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110038I05Rik antibody
    • AI314632 antibody
    • Aldehyde dehydrogenase 6 family member A1 antibody
    • Aldehyde dehydrogenase family 6 member A1 antibody
    • Aldehyde dehydrogenase family 6, subfamily A1 antibody
    • ALDH6A1 antibody
    • Malonate semialdehyde dehydrogenase antibody
    • Malonate-semialdehyde dehydrogenase [acylating] antibody
    • Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody
    • Methylmalonate-semialdehyde dehydrogenase [acylating] antibody
    • MGC37325 antibody
    • MGC40271 antibody
    • Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody
    • mitochondrial antibody
    • MMSA_HUMAN antibody
    • MMSADHA antibody
    • MMSDH antibody
    see all

Anti-ALDH6A1 antibody images

  • Anti-ALDH6A1 antibody (ab109576) at 0.1 µg/ml + Mouse kidney lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 58 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)

References for Anti-ALDH6A1 antibody (ab109576)

ab109576 has not yet been referenced specifically in any publications.

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