Overview

  • Product nameAnti-ALDH6A1 antibody
    See all ALDH6A1 primary antibodies
  • Description
    Goat polyclonal to ALDH6A1
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Dog, Pig
  • Immunogen

    Synthetic peptide:

    C-SRSSFRGDTN

    , corresponding to internal sequence amino acids 487-496 of Human ALDH6A1 (NP_005580.1).

  • Positive control
    • Human, Mouse and Rat Kidney lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab109582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 58 kDa.

Target

  • FunctionPlays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
  • Involvement in diseaseDefects in ALDH6A1 are the cause of methylmalonate semialdehyde dehydrogenase deficiency (MMSDH deficiency) [MIM:603178]. This is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
  • Sequence similaritiesBelongs to the aldehyde dehydrogenase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110038I05Rik antibody
    • AI314632 antibody
    • Aldehyde dehydrogenase 6 family member A1 antibody
    • Aldehyde dehydrogenase family 6 member A1 antibody
    • Aldehyde dehydrogenase family 6, subfamily A1 antibody
    • ALDH6A1 antibody
    • Malonate semialdehyde dehydrogenase antibody
    • Malonate-semialdehyde dehydrogenase [acylating] antibody
    • Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody
    • Methylmalonate-semialdehyde dehydrogenase [acylating] antibody
    • MGC37325 antibody
    • MGC40271 antibody
    • Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody
    • mitochondrial antibody
    • MMSA_HUMAN antibody
    • MMSADHA antibody
    • MMSDH antibody
    see all

Anti-ALDH6A1 antibody images

  • ab109582 (5µg/ml) shows staining of ALDH6A1 in paraffin embedded Human Liver following steamed antigen retrieval with citrate buffer pH 6 and AP-staining. This shows textured staining of the cytoplasm consistent with mitochondria.

  • Anti-ALDH6A1 antibody (ab109582) at 0.1 µg/ml + Mouse Kidney lysate (in RIPA buffer) at 35 µg

    Predicted band size : 58 kDa

References for Anti-ALDH6A1 antibody (ab109582)

ab109582 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab109582.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"