• Product name
  • Description
    Rabbit polyclonal to ALDH6A1
  • Tested applications
    Suitable for: WB, ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    A KLH conjugated synthetic peptide from the N-terminal region of human ALDH6A1.

  • Positive control
    • This antibody gave a positive result in IF/ICC when used in the following formaldehyde fixed cell lines: T47D.



Our Abpromise guarantee covers the use of ab63181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 58 kDa.
ELISA 1/1000.
IHC-P 1/10 - 1/50.
ICC/IF Use at an assay dependent concentration. PubMed: 20966424


  • Function
    Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
  • Involvement in disease
    Defects in ALDH6A1 are the cause of methylmalonate semialdehyde dehydrogenase deficiency (MMSDH deficiency) [MIM:603178]. This is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
  • Sequence similarities
    Belongs to the aldehyde dehydrogenase family.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110038I05Rik antibody
    • AI314632 antibody
    • Aldehyde dehydrogenase 6 family member A1 antibody
    • Aldehyde dehydrogenase family 6 member A1 antibody
    • Aldehyde dehydrogenase family 6, subfamily A1 antibody
    • ALDH6A1 antibody
    • Malonate semialdehyde dehydrogenase antibody
    • Malonate-semialdehyde dehydrogenase [acylating] antibody
    • Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody
    • Methylmalonate-semialdehyde dehydrogenase [acylating] antibody
    • MGC37325 antibody
    • MGC40271 antibody
    • Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody
    • mitochondrial antibody
    • MMSA_HUMAN antibody
    • MMSADHA antibody
    • MMSDH antibody
    see all

Anti-ALDH6A1 antibody images

  • ab63181 staining of human breast carcinoma tissue by formalin-fixed and parrafin-embedded IHC.    
  • Anti-ALDH6A1 antibody (ab63181) at 1/50 dilution + T47D cell lysate at 35 µg

    Predicted band size : 58 kDa
  • ICC/IF image of ab63181 stained T47D cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab63181 at 1µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

References for Anti-ALDH6A1 antibody (ab63181)

This product has been referenced in:
  • Suryawanshi AR  et al. Epididymosome Mediated Acquisition of MMSDH an Androgen Dependent and Developmentally Regulated Epididymal Sperm Protein. J Androl : (2011). WB, IHC-P ; Rat . Read more (PubMed: 22207704) »
  • Suryawanshi AR  et al. Differential Proteomics Leads to Identification of Domain Specific Epididymal Sperm Proteins. J Androl : (2010). WB, ICC/IF ; Human, Rat . Read more (PubMed: 20966424) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab63181.
Please use the links above to contact us or submit feedback about this product.


Sign up