Overview

  • Product nameAnti-ALDH6A1 antibody
    See all ALDH6A1 primary antibodies
  • Description
    Mouse polyclonal to ALDH6A1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human ALDH6A1 (NP_005580.1)

  • Positive control
    • Human liver tissue lysate and ALDH6A1 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab89629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa.

Target

  • FunctionPlays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
  • Involvement in diseaseDefects in ALDH6A1 are the cause of methylmalonate semialdehyde dehydrogenase deficiency (MMSDH deficiency) [MIM:603178]. This is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
  • Sequence similaritiesBelongs to the aldehyde dehydrogenase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110038I05Rik antibody
    • AI314632 antibody
    • Aldehyde dehydrogenase 6 family member A1 antibody
    • Aldehyde dehydrogenase family 6 member A1 antibody
    • Aldehyde dehydrogenase family 6, subfamily A1 antibody
    • ALDH6A1 antibody
    • Malonate semialdehyde dehydrogenase antibody
    • Malonate-semialdehyde dehydrogenase [acylating] antibody
    • Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody
    • Methylmalonate-semialdehyde dehydrogenase [acylating] antibody
    • MGC37325 antibody
    • MGC40271 antibody
    • Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody
    • mitochondrial antibody
    • MMSA_HUMAN antibody
    • MMSADHA antibody
    • MMSDH antibody
    see all

Anti-ALDH6A1 antibody images

  • Anti-ALDH6A1 antibody (ab89629) at 1 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 58 kDa
    Observed band size : 52 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-ALDH6A1 antibody (ab89629) at 1 µg/ml

    Lane 1 : ALDH6A1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 58 kDa
    Observed band size : 58 kDa

References for Anti-ALDH6A1 antibody (ab89629)

ab89629 has not yet been referenced specifically in any publications.

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