Overview

  • Product name
  • Description
    Goat polyclonal to ALDH9A1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide:

    C-QKEILDKFTEEVVKQ

    , corresponding to internal sequence amino acids 321-334 of Human ALDH9A1 (NP_000687.3).

  • Positive control
    • Human kidney lysate, Human liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab103898 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 54 kDa.
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction.
  • Tissue specificity
    High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.
  • Pathway
    Amine and polyamine biosynthesis; carnitine biosynthesis.
  • Sequence similarities
    Belongs to the aldehyde dehydrogenase family.
  • Developmental stage
    Strongly expressed in human embryonic brain (gestational age 12 weeks).
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4 trimethylaminobutyraldehyde dehydrogenase antibody
    • 4-trimethylaminobutyraldehyde dehydrogenase antibody
    • AL9A1_HUMAN antibody
    • aldehyde dehydrogenase (NAD+) antibody
    • Aldehyde dehydrogenase 9A1 antibody
    • Aldehyde dehydrogenase E3 isozyme antibody
    • Aldehyde dehydrogenase family 9 member A1 antibody
    • ALDH4 antibody
    • ALDH7 antibody
    • ALDH9 antibody
    • aldh9A1 antibody
    • E3 antibody
    • Gamma aminobutyraldehyde dehydrogenase antibody
    • Gamma-aminobutyraldehyde dehydrogenase antibody
    • R aminobutyraldehyde dehydrogenase antibody
    • R-aminobutyraldehyde dehydrogenase antibody
    • TMABADH antibody
    see all

Images

  • ab103898 (3.8µg/ml) staining of paraffin embedded Human Cerebellum following Steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows staining of a few cells between the Granular Cell layer and the Molecular Layer of the Cerebellum, note the unstained Purkinje cell at 10 O'clock.

  • Anti-ALDH9A1 antibody (ab103898) at 0.3 µg/ml + Human kidney lysate at 35 µg

    Predicted band size : 54 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

References

ab103898 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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