Overview

  • Product nameAnti-ALDOB antibody
    See all ALDOB primary antibodies
  • Description
    Rabbit polyclonal to ALDOB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 108-157 (KLDQGGAPLA GTNKETTIQG LDGLSERCAQ YKKDGVDFGK WRAVLRIADQ) of Human ALDOB (NP_000026).

  • Positive control
    • Human fetal liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab83403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • PathwayCarbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.
  • Involvement in diseaseDefects in ALDOB are the cause of hereditary fructose intolerance (HFI) [MIM:229600]. HFI is an autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life.
  • Sequence similaritiesBelongs to the class I fructose-bisphosphate aldolase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALDB antibody
    • ALDO B antibody
    • ALDO2 antibody
    • ALDOB antibody
    • ALDOB_HUMAN antibody
    • Aldolase 2 antibody
    • Aldolase B antibody
    • Aldolase B fructose bisphosphate antibody
    • Aldolase2 antibody
    • AldolaseB antibody
    • EC 4.1.2.13 antibody
    • Fructose bisphosphate aldolase B antibody
    • Fructose-bisphosphate aldolase B antibody
    • Liver type aldolase antibody
    • Liver-type aldolase antibody
    • MS1077 antibody
    see all

Anti-ALDOB antibody images

  • Anti-ALDOB antibody (ab83403) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal liver lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 39 kDa
    Observed band size : 39 kDa
    Additional bands at : 42 kDa. We are unsure as to the identity of these extra bands.

References for Anti-ALDOB antibody (ab83403)

ab83403 has not yet been referenced specifically in any publications.

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