Overview

  • Product nameAnti-Aldolase B antibody [19]
    See all Aldolase B primary antibodies
  • Description
    Mouse monoclonal [19] to Aldolase B
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human Aldolase B. Recombinant human ALDOB expressed in an E.coli expression system

  • Positive control
    • Human recombinant ALDOB protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab67222 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 49 kDa (predicted molecular weight: 39 kDa).
ELISA Use at an assay dependent dilution.

Target

  • PathwayCarbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.
  • Involvement in diseaseDefects in ALDOB are the cause of hereditary fructose intolerance (HFI) [MIM:229600]. HFI is an autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life.
  • Sequence similaritiesBelongs to the class I fructose-bisphosphate aldolase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALDB antibody
    • ALDO B antibody
    • ALDO2 antibody
    • ALDOB antibody
    • ALDOB_HUMAN antibody
    • Aldolase 2 antibody
    • Aldolase B antibody
    • Aldolase B fructose bisphosphate antibody
    • Aldolase2 antibody
    • AldolaseB antibody
    • EC 4.1.2.13 antibody
    • Fructose bisphosphate aldolase B antibody
    • Fructose-bisphosphate aldolase B antibody
    • Liver type aldolase antibody
    • Liver-type aldolase antibody
    • MS1077 antibody
    see all

Anti-Aldolase B antibody [19] images

  • Anti-Aldolase B antibody [19] (ab67222) at 1/1000 dilution + Human recombinant ALDOB protein

    Predicted band size : 39 kDa
    Observed band size : 49 kDa (why is the actual band size different from the predicted?)
    This antibody has only been tested against the recombinant protein fragment in Western blot.

References for Anti-Aldolase B antibody [19] (ab67222)

ab67222 has not yet been referenced specifically in any publications.

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