Overview

  • Product nameAnti-ALG11 antibody
    See all ALG11 primary antibodies
  • Description
    Rabbit polyclonal to ALG11
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide designed within residues: LSEDLGVQEY VEFKINIPFD ELKNYLSEAT IGLHTMWNEH FGIGVVECMA, corresponding to internal amino acids 360-409 of Human ALG11 (NP_001004127)

  • Positive control
    • HepG2 cell lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab84123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain.
  • Involvement in diseaseDefects in ALG11 are the cause of congenital disorder of glycosylation type 1P (CDG1P) [MIM:613661]. A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • Sequence similaritiesBelongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  • Cellular localizationEndoplasmic reticulum. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI849156 antibody
    • alg11 antibody
    • ALG11_HUMAN antibody
    • Asparagine-linked glycosylation 11 antibody
    • Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) antibody
    • Asparagine-linked glycosylation protein 11 homolog antibody
    • AW492253 antibody
    • B230397C21 antibody
    • GT8 antibody
    • KIAA0266 antibody
    • OTTMUSP00000022781 antibody
    • RGD1564725 antibody
    see all

Anti-ALG11 antibody images

  • Anti-ALG11 antibody (ab84123) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 56 kDa
    Observed band size : 56 kDa

References for Anti-ALG11 antibody (ab84123)

ab84123 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"