Overview

  • Product nameAnti-ALG9 antibody
    See all ALG9 primary antibodies
  • Description
    Rabbit polyclonal to ALG9
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide between amino acids 532-559 from the C terminal region of Human ALG9 (NP_001071159.1, NP_001071160.1, NP_001071158.1, NP_079016.2).

  • Positive control
    • Ramos cell line lysates

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG

Applications

Our Abpromise guarantee covers the use of ab107072 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 70 kDa.

Target

  • FunctionCatalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
  • Tissue specificityUbiquitously expressed; with highest levels in heart, liver and pancreas.
  • PathwayProtein modification; protein glycosylation.
  • Involvement in diseaseNote=A chromosomal aberration involving ALG9 is found in a family with bipolar affective disorder. Translocation t(9;11)(p24;q23). However, common variations in ALG9 do not play a major role in predisposition to bipolar affective disorder.
    Defects in ALG9 are the cause of congenital disorder of glycosylation type 1L (CDG1L) [MIM:608776]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • Sequence similaritiesBelongs to the glycosyltransferase 22 family.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALG9 antibody
    • ALG9_HUMAN antibody
    • Alpha-1,2-mannosyltransferase ALG9 antibody
    • Asparagine-linked glycosylation protein 9 homolog antibody
    • Disrupted in bipolar disorder protein 1 antibody
    see all

Anti-ALG9 antibody images

  • Anti-ALG9 antibody (ab107072) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 70 kDa

References for Anti-ALG9 antibody (ab107072)

ab107072 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"