For the best experience on the Abcam website please upgrade to a modern browser such as
Rabbit polyclonal to ALKBH8
ab113512 is also predicted to react with isoform 4 of Human ALKBH8 (76kDa).
Predicted to work with:
Recombinant fragment, corresponding to N terminal amino acids 2-238 of Human ALKBH8 (BC015183).
Human fetal spleen and A549 cell lysates; Human fetal spleen tissue.
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide Constituents: 98% PBS, 1% BSA
Concentration information loading...
Immunogen affinity purified
ab113512 is purified by a protein affinity column.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 75 kDa.
1/100 - 1/500.
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
Widely expressed, with highest expression in spleen, followed by pancreas and lung.
Belongs to the alkB family.
Contains 1 Fe2OG dioxygenase domain. Contains 1 RRM (RNA recognition motif) domain.
Cytoplasm. Nucleus. Predominantly cytoplasmic.
Information by UniProt
Western blot - ALKBH8 antibody (ab113512)
All lanes : Anti-ALKBH8 antibody (ab113512) at 1/500 dilution Lane 1 : Human fetal spleen lysate Lane 2 : A549 cell lysate Predicted band size : 75 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ALKBH8 antibody (ab113512)
ab113512 at 1/100 dilution staining ALKBH8 in Formalin-fixed, Paraffin-embedded Human fetal spleen tissue by Immunohistochemistry.
Note cytoplasmic and nuclear staining.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"