Overview

  • Product name
  • Description
    Rabbit polyclonal to ALKBH8
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the C-terminal region of Human ALKBH8 conjugated to KLH (NP_620130).

  • Positive control
    • HL60 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab91482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: 1/1000.
    WB: 1/50 - 1/100. Predicted molecular weight: 75 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
    • Tissue specificity
      Widely expressed, with highest expression in spleen, followed by pancreas and lung.
    • Sequence similarities
      Belongs to the alkB family.
      Contains 1 Fe2OG dioxygenase domain.
      Contains 1 RRM (RNA recognition motif) domain.
    • Cellular localization
      Cytoplasm. Nucleus. Predominantly cytoplasmic.
    • Information by UniProt
    • Database links
    • Alternative names
      • 4930562C03Rik antibody
      • 8030431D03Rik antibody
      • 9430088N01Rik antibody
      • ABH8 antibody
      • alkB alkylation repair homolog 8 (E. coli) antibody
      • alkB alkylation repair homolog 8 antibody
      • AlkB homologue 8 antibody
      • ALKB8_HUMAN antibody
      • ALKBH8 antibody
      • Alkylated DNA repair protein alkB homolog 8 antibody
      • FLJ38204 antibody
      • MGC10235 antibody
      • OTTHUMP00000211286 antibody
      • OTTHUMP00000211287 antibody
      • Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody
      • RGD1304687 antibody
      • S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody
      • tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody
      see all

    Images

    • Anti-ALKBH8 antibody (ab91482) at 1/50 dilution + HL60 cell line lysate at 35 µg

      Predicted band size : 75 kDa

    References

    ab91482 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab91482.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up