Anti-alpha 1 Fetoprotein Receptor antibody [5E1] (ab8276)

Overview

  • Product nameAnti-alpha 1 Fetoprotein Receptor antibody [5E1]
    See all alpha 1 Fetoprotein Receptor primary antibodies
  • Description
    Mouse monoclonal [5E1] to alpha 1 Fetoprotein Receptor
  • SpecificityReacts with different determinants of human alpha-fetoprotein receptor.
  • Tested applicationsWB, ICC, ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human).

  • Positive control
    • The following cultured tumor cells were used as positive controls: ovarian adenocarcinoma SKOV3, human mammary carcinoma MCF-7, human cervical carcinoma Hela, B-cell lymphoma Raji and T-cell lymphoma Jurkat. Negative immunoreactivity with AFP receptor should be shown with normal non-stimulated freshly prepared human peripheral blood lymphocytes without monocytes and granulocytes (not to incubate with fetal serum).

Properties

Applications

Our Abpromise guarantee covers the use of ab8276 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution.
ICC Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution. Capture
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [2B8] to alpha 1 Fetoprotein Receptor (ab37207). Capture

Target

  • RelevanceAFP's cell growth-regulatory effects are mediated by its specific plasma membrane receptors coupled with its transmembrane signaling transduction through the pathway of cAMP-PKA and intracellular calcium to regulate the expression of oncogenes. The properties of the AFP receptor as well as the subsequent events after AFP binding are still undefined.
  • Alternative names
    • AFP receptor antibody
    • Alpha fetoprotein receptor antibody

References for Anti-alpha 1 Fetoprotein Receptor antibody [5E1] (ab8276)

ab8276 has not yet been referenced specifically in any publications.

Product Wall

Having reviewed our catalog of anti-alpha 1 Fetoprotein antibodies suitable for use in ELISA, I have found the following 2 pairs which have been verified by us. AB8276 pairs with ab37207. More information about these items may be found at: Ab8276...

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Thank you for your patience with this reply.

Our supplying laboratory confirmed that according to their results our ab8276 [5E1] and ab37207 [2B8] are specific to AFP receptor. He has checked a lot of tumorous samples (tissues and cells) by u...

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We do not have so far found publications that list this antibody which can be due to the fact that the catalog numbers are often not published.

I also checked with the supplying lab and they let me know that unfortunately we have not publ...

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Thank you for your enquiry and your interest.

Currently, we only sell these two antibodies (ab8276, ab37207) against alpha 1 Fetoprotein Receptor unconjugated. Both have been tested in human samples; the cross-reactivity with other species ha...

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Thank you for your enquiry. The concentration of this antibody varies lot-to-lot. A general concentration range is between 3-5 mg/ml. If you could reply to this email with the lot number you have, I can get an exact concentration for you. I apolo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"